Program

2025 Symposium Program

Check back on this web page to see the details of titles, talks, and speakers as they become available. This page will be regularly updated starting in June 2025 through December.

Tuesday, December 9

(All times are in Central Standard Time)

Ancillary Educational Events
(In-person only, not available for online or virtual viewing)

7:45 – 9:15 am

CBCS - Chinese Breast Cancer Society
Location:
Room 301ABC

8:00 – 9:30 am

Lilly Advocate Program
Location: Room 220ABC

9:30 – 10:45 am

ABC Global Alliance Ten Year Breast Cancer Report
Location: Room 221ABC

9:30 – 11:00 am

St. Galan Updates
Location: Room 301ABC

SABCS Program Begins

11:00 am – 12:30 pm

Trainee Workshop: Enhanced Research and Community Impact
Location: 221ABC

11:00 am – 12:30 pm

Special Session 1 - Open Bar and All you Can Eat? The Impact of Lifestyle in Breast Cancer Risk and Recurrence

Location: Stars at Night 1 & 2

Moderator: Seema Khan, MD, MS, Northwestern University Feinberg School of Medicine, Chicago

11:00 AM - 11:25 AM - Topic 1: Alcohol, genetics of alcohol metabolism and breast cancer risk

  • Julia Palmer, ScD, Boston University, Boston

11:25 AM - 11:55 AM - Topic 2: Effects of alcohol consumption and cessation on breast cancer risk

  • Mary Beth Terry, PhD, Columbia University, New York

11:55 AM - 12:15 PM - Topic 3: Obesity and Breast Cancer- the molecular link

  • Kristy Brown, PhD, University of Kansas Medical Center, Kansas City, Kansas

Patient Advocate: Stacey Tinianov, MPH, BCPA, Advocates for Collaborative Education, Santa Cruz, California

12:15 PM - 12:30 PM  Panel Q&A

11:00 am – 12:30 pm

Special Session 2: Lobular Breast Cancer Updates
Location: Stars at Night 3 & 4

Moderator: Steffi Oesterreich, PhD, UPMC Hillman Cancer Center, Pittsburgh & Marleen Kok, MD, PhD, Netherlands Cancer Institute, Amsterdam

11:10 AM - 11:25 Topic 1: Current updates on diagnostic criteria and classification of special subtypes

  • Anne Vincent-Salomon, PhD, Institut Curie, Paris

11:25 AM - 11:40 AM Topic 2: Novel biomarkers with clinical implications

  • Christos Sotiriou, MD, PhD, Institut Jules Bordet, Anderlecht, Belgium

11:40 AM - 11:55 AM Topic 3: Controversies in clinical decision making – is there still a role for chemotherapy?

  • Otto Metzger, MD, Dana-Farber Cancer Institute, Boston

11:55 AM - 12:10 PM Topic 4: LC-specific trials: lessons learned and future designs

  • Philipe Aftimos, MD, Insitut Jules Bordet, Anderlecht, Belgium

12:10 PM - 12: 30 PM Panel discussion

Patient Advocate: Flora Migyanka, BA, Dynami Foundation

11:00 am – 12:30 pm

Special Session 3: Breast Cancer in Young Women: Biology, Treatment, and Ethics
Location: TBD

Moderator: Ann Partridge, MD, MPH, Dana-Farber Cancer Institute, Boston

11:00 AM - 11:30 AM Topic 1: Epidemiology and Biology of Young Onset Breast Cancer

  • Virginia Borges, MD, UCHealth Diane O’Connor Thompson Breast Center – Anschutz Medical Campus, Aurora, Colorado

11:30 AM - 12:00 PM Topic 2: Special Management Considerations for Young Patients with Breast Cancer

  • Yara Abdou, MD, MSCR, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

12:00 PM - 12:30 PM Topic 3: Ethical Issues in the Care of Young Patients with Breast Cancer

  • Lisa Campo-Engelstein, PhD, University of Texas Medical Branch, Galveston, Texas
12:45 – 2:15 pm

Translational Workshop 1: Spatial Omics for Prediction, Prognostication, and Mechanistic Insights
Location: Stars at Night 1-2

Moderator: Leif Ellisen, MD, PhD, Harvard University, Cambridge, Massachusetts

12:45 PM -1:10 PM Topic 1: Proteomics

  • Sandro Santagata, MD, PhD, Harvard Medical School, Cambridge, Massachusetts

1:10 PM - 1:35 PM Topic 2: Metabolomics+

  • Ralph Deberardinis, MD, PhD, UT Southwestern, Dallas

1:35 PM - 2:00 PM Topic 3: Gylcocomics

  • TBD

2:00 PM - 2:15 PM Panel discussion

 Patient advocate: Jane Perlmutter, PhD

12:45 – 2:15 pm

Translational Workshop 2: Liquid Biopsy in Breast Cancer, Bridging Technology and Clinical Practice
Location: 
Stars at Night 3-4

Moderator: Pedram Razavi, MD, PhD, Memorial Sloan Kettering Cancer Center, New York

12:45 PM - 1:10 PM Topic 1: Emerging technologies in liquid biopsy

  • Maximilian Diehn, MD, PhD, Stanford University, Stanford, California

1:10 PM - 1:35 PM Topic 2: Expanding clinical application of liquid biopsy in breast cancer

  • Pedram Razavi, MD, PhD, Memorial Sloan Kettering Cancer Center, New York 

1:35 PM - 2:00 PM Topic 3: Utilizing liquid biopsy for detection and monitoring CNS metastases

  • Alexandra Miller, MD, PhD, NYU Langone Health Perlmutter Cancer Center, New York

2:00 PM - 2:15 PM Panel discussion

Patient advocate: Michelle Tregear, National Breast Cancer Coalition

12:45 – 2:15 pm

Clinical Workshop 1: Risk Assessment and Management in Young Women
Location:
Hemisfair Ballroom 1-2

12:45 PM - 12:55 PM Moderator: Sonya Reid, MD, MPH, Vanderbilt-Ingram Cancer Center, Nashville

12:55 PM - 1:10 PM Topic 1: Surveillance strategies for young women – when and how often?

  • Allison Kurian, MD, M.Sc, Stanford Medicine, Stanford, California

1:10 PM - 1:25 PM Topic 2: Novel imaging strategies for young women – looking to the future

  • Emily Conant, MD, University of Pennsylvania Perelman School of Medicine, Philadelphia

1:25 PM - 1:40 PM Topic 3: Should management of atypia in young women differ?

  • Laura K. Harper, Mayo Clinic, Phoenix, Arizona

1:40 PM - 1:55 PM Topic 4: Considerations for Prevention – balancing fertility and risk

  • Seema Kahn, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago

1:55 PM - 2:15 PM Panel discussion

Patient Advocate: Vernal Branch, Independent Research Patient Advocatie, Richmond, Virginia

12:45 – 2:15 pm

Careeer Development: Compassionate Leadership Workshop
Location:
221ABC

Speaker: Anne Welsh

2:30 – 4:15 pm

Educational Session 1: After CDK4/6 Inhibitors: Advancing Treatment for HR+HER2-negative Metastatic Breast Cancer
Location: Stars at night 1-2

Moderator: Antoinette Tan, MD, MHS, Wake Forest University School of Medicine, Charlotte, North Carolina

2:30 PM - 3:00 PM Topic 1: Treatment Strategies after CDK4/6 Inhibitor Progression

  • Mafalda Oliveira, MD, PhD, Vall d'Hebron Hospital, Barcelona

3:00 PM - 3:30 PM Topic 2: Next Generation Endocrine Agents

  • Erica Mayer, MD, MPH, Dana-Farber Cancer Institute, Boston

3:30 PM - 4:00 PM Topic 3: Emerging Agents to Overcome CDK4/6 Inhibitor Resistance

  • Shom Goel, PhD, FRACP, Peter MacCallum Cancer Centre, Melbourne, Australia

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Abigail Johnston, SurvivingBreastCancer.org, Orlando, Florida

2:30 – 4:15 pm

Educational Session 2: Dormancy and Re-activation of Breast Cancer Cells at Distant Metastatic Sites
Location:
221 ABC

Moderator: Heide Ford, PhD, University of Colorado School of Medicine, Denver

2:30 PM - 3:00 PM - Topic 1: Viral reactivation of dormant breast cancer

  • Mercedes Rincon, PhD, University of Colorado School of Medicine, Aurora, Colorado

3:00 PM - 3:30 PM Topic 2: Role of alveolar macrophages in dormancy

  • Xue-Yan He, PhD, Washington University in St. Louis

3:30 PM - 4:00 PM Topic 3: In vivo mechanisms regulating cellular dormancy and tumor recurrence

  • Lewis Chodosh, PhD, University of Pennsylvania Perelman School of Medicine, Philadelphia

4:00 PM - 4:15 PM Panel Discussion

Patient Advocate: Lynda Weatherby, Metastatic Breast Cancer Alliance, Seattle

2:30 – 4:15 pm

Educational Session 3: Refining Local Therapy in Multi-disciplinary Care
Location:
Stars at Night 3-4

Moderator: Jonathan Strauss, MD, MBA, Roberts H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago

2:30 PM - 3:00 PM Topic 1: Repeat Breast Conservation with reirradiation – what’s the data and how do we do it?

  • Chelain Goodman, MD, PhD, MD Anderson Cancer Center, Houston

3:00 PM - 3:30 PM Topic 2: Should we irradiate the IM Nodes: Settling the Issue

  • Birgitte Offersen, MD,  Aarhus University Department of Oncology, Aarhus, Denmark

3:30 PM - 4:00 PM Topic 3: The Truth About Radiotherapy and Reconstruction

  • Justin Broyles, MD, Brigham and Women’s Hospital, Boston

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Judy Fitzgerald, Sisters4Prevention, Delray Beach, Florida

2:30 – 4:15 pm

Educational Session 4: Balancing Act: Hormone Replacement Therapy in Breast Cancer Care
Location: Hemisfair Ballroom 1-2

Moderator: Tara Sanft, MD, Yale School of Medicine, New Haven, Connecticut

2:30 PM - 3:00 PM Topic 1: "HRT and Breast Cancer: How History Shaped Fear and What Comes Next" Re-examining past research, debunking myths, and guiding future recommendations

  • Maryam Lustberg, MD, MPH, Yale School of Medicine, New Haven, Connecticut

3:00 PM - 3:30 PM Topic 2: "Navigating the Latest HRT Guidelines: What Leading Medical Societies Say" A comprehensive review of updated recommendations from major health organizations.

  • Juliana Kling, MD, MPH, MACP, MSCP, Mayo Clinic, Phoenix

3:30 PM - 4:00 PM Topic 3: "HRT Across the Breast Cancer Spectrum: Risks, Benefits, and Considerations" Exploring HRT use in high-risk individuals, survivors, and different breast cancer subtypes.

  • Lisa Larkin, MD, FACP, MSCP, Ms. Medicine/HERmedicine, Cincinnati, Ohio

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Thelma Perry Brown, BS, Patient Research Advocate, Birmingham, Alabama

2:30 – 4:15 pm

Educational Session 5: Best of AACR
Location:
Hemisfair Ballroom 3

2:30 PM - 2:50 PM Topic 1: The Influence of ecDNA in Cancer

2:50 PM - 3:10 PM Topic 2: State of RAS Inhibitor Field

3:10 PM - 3:30 PM Topic 3: Decoding the archetypes and ecotypes of triple-negative breast cancer in responses to chemotherapy

3:30 PM - 3:50 PM Topic 4: An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer

3:50-4:10 Topic 5: Metastatic dissemination from the perspective of the cancer cell, its microenvironment, and the Host

4:30 – 5:30 pm

Rapid Fire 1
Location:
Stars at Night 1-2

5:15 – 5:45 pm

Refreshment Break and Networking
Location:
TBD

5:45 – 6:45 pm

Rapid Fire 2
Location:
Stars at Night 1-2

Wednesday, December 10

(All times are in Central Standard Time)

7:00 – 8:30 am

Poster Spotlight 1
Location: Hemisfair Ballroom 3

Moderator:

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

7:00 – 8:30 am

Poster Spotlight 2
Location: 301 ABC

Moderator:

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50-8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

7:00 – 8:30 am Poster Spotlight 3

Location: 302 ABC

Moderator:

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

7:00 – 8:30 am Poster Spotlight 4

Location: 221 ABC

Moderator:

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30-7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

8:45 am – 9:30 am

Opening Remarks and McGuire Award
Location:
Hall 1

  • Opening Remarks from Symposium Co-Chairs Dr. Carlos Arteaga and Dr. Virginia Kaklamani
  • McGuire Award presentation and lecture
9:30 am – 12:00 pm

General Session 1
Location:
Hall 1

12:00 – 6:45 pm 

Exhibition Hall Open

12:00 – 12:30 pm 

Break

12:00 – 12:50 pm

Clinical Case Discussion
Location: Stars at Night 1 & 2

Moderator: Hal Burstein, MD, PhD, Dana-Farber Cancer Institute, Boston

Panel members:

  • William Gradishar, Feinberg School of Medicine, Northwester University, Chicago
  • Olga Kantor, MD, MS, Dana-Farber Cancer Institute, Boston
  • Hannah Yong Wen, MD, PhD, Memorial Sloan Kettering Cancer Center, New York 

Patient Advocate: Ginny Mason, Inflammatory Breast Cancer Research Foundation

12:30 – 2:00 pm

Poster Session 1
Location:
Exhibition Hall

1:00 – 2:15 pm

State of the Art 1 - Refining Risk and Tailoring Treatment: Liquid Biopsy for Adaptive Therapy in Breast Cancer
Location: Stars at Night 1 & 2

1:00 PM - 1:10 PM Moderator: David Cescon, MD, Princess Margaret Cancer Centre, Toronto 

Topic 1: Neoadjuvant adaptive strategies: integrating imaging and ctDNA to personalize preoperative therapy

  • Angie DeMichele, MD, MSCE, University of Pennsylvania Perelman School of Medicine, Philadelphia

Topic 2: MRD-Informed Adjuvant Therapy: From Risk Stratification to Personalized Management

  • Michail Ignatiadis, MD, PhD, Institut Jules Bordet, Anderlecht, Belgium

Topic 3: Guiding Metastatic Breast Cancer Treatment with Dynamic and Predictive Liquid Biopsy Biomarkers

  • François-Clément Bidard, MD, PhD, Institut Curie, Paris

Patient Advocate: Tracy Leduc Solak

1:00 – 2:15 pm

Translational Controversies: : ADCs, Targeted Therapy or Chemo?
Location: Stars at Night 3 & 4

Moderator: David Rimm, MD, PhD, Yale School of Medicine, New Haven, Connecticut

1:05 - 1:25 Topic 1: HER2 low/ultralow; What the pathologist sees

  • Dennis Sgroi, MD, Harvard University, Cambridge, Massachusetts

1:25 -1:45 Topic 2: Evidence that ADCs are target therapy

  • Sarat Chandarlapaty, MD, PhD, Memorial Sloan Kettering Cancer Center, New York

1:45 - 2:05 Topic 3: Evidence that ADCs are chemotherapy

  • Sara Hurvitz, MD, FACP, Fred Hutchinson Cancer Center, Seattle, Washington                
2:30 – 4:15 pm

Educational Session 6: ADCs in the Clinic

Location: Stars at Night 1 & 2

Moderator: Adrienne Waks, MD, Dana-Farber Cancer Institute, Boston

2:30 PM - 3:00 PM Topic 1: Moving on up: ADCs in early - stage breast cancer

  • Sibylle Loibl, MD, CEO of the German Breast Group Forschungs GmbH, Frankfurt, Germany

3:00 PM - 3:30 PM Topic 2: Positioning and sequencing of ADCs in metastatic breast cancer

  • Reshma Mahtani, DO, Miami Cancer Institute, Miami

3:30 PM - 4:00 PM Topic 3: Activity of ADCs in patients with brain metastases

  • Andrew Brenner, MD, PhD, UT Health San Antonio

Patient Advocate: Rosa Olmos, Barcelona, Spain 

Panel Q&A

2:30 – 4:15 pm

Educational Session 7: Immune Microenvironment
Location: Hemisfair Ballrooom 3

Moderator: Charles Perou, PhD , Lineberger Comprehensive Cancer Center University of North Carolina

2: 30 - 3:00 PM Topic 1: Immune cell changes across the lifespan in ER+ breast cancers

  • TBD

3:30 - 3:30 PM Topic 2: Immune system role in early onset breast cancer

  • Virginia Borges, MD, UCHealth Diane O’Connor Thompson Breast Center – Anschutz Medical Campus, Aurora, Colorado

3:30 PM - 4:00 PM Topic 3: Glucocorticoid and T-cell receptors in breast cancer

  •  Suzanne Conzen, MD, UT Southwestern, Dallas

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Ghecemy Lopez, DSW, MAED, USC Norris Comprehensive Cancer Center, Los Angeles

2:30 – 4:15 pm

Educational Session 8: Optimizing De-escalation in Low-Risk HR+ Early-Stage Breast Cancer
Location: Stars at Night 3 & 4

Moderator: Mylin Torres, MD, Winship Cancer Institute of Emery University, Atlanta

2:30 PM - 3:00 PM Topic 1: Advances in Breast Radiotherapy – Less is More

  • Jonathan Strauss, MD, MBA, Roberts H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago

3:00 PM - 3:30 PM Topic 2: Radiation therapy or Endocrine therapy – which one to omit?

  • Icro Meattini, MD, University of Florence, Florence, Italy

3:30 PM - 4:00 PM Topic 3: What do we do with the nodes?

  • Tari King, MD, FACS, Dana-Farber Cancer Institute, Boston

4:00 PM - 4:15 PM Panel Q&A

  • Patient Advocate: Marylinn Minor, Virginia Breast Cancer Foundation Board Member
2:30 – 4:15 pm

Educational Session 9: Management for Predisposition Gene Carriers
Location: 221 ABC

Moderator: Susan Domchek, MD, University of Pennsylvania Perelman School of Medicine, Philadelphia

2:30 PM - 3:00 PM Topic 1: Overview of genetic risk models

  • Tuya Pal, MD, Vanderbilt-Ingram Cancer Center, Nashville

3:00 PM - 3:30 PM Topic 2: Interpretation of inherited alterations in high and moderate risk genes

  • Fergus Couch, PhD, Mayo Clinic, Rochester, Minnesota

3:30 PM - 4:00 PM Topic 3: Clinical management of predisposition gene carriers

  • Stephanie Wong, MD, MPH, McGill Medical School, Montreal

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Bri Wesley-Majsiak, Co-founder of The Breasties, Los Angeles

2:30 – 4:15 pm

Educational Session 10: Rare Tumor Types
Location: Hemisfair Ballroom 1 & 2

Moderator: William Gradishar, MD, Northwestern University Feinberg School of Medicine, Chicago

2:30 PM - 3:00 PM Topic 1: How to optimally treat Phyllodes tumors 

  • Lauren Rosenberger, MD, MS, Duke University Cancer Institute, Durham, North Carolina

3:00 PM - 3:30 PM Topic 2: Pathological Characterization of Rare tumor types

  • TBD

3:30 PM - 4:00 PM Topic 3: Metaplastic Breast Cancer

  • Jenny Chang, MD, Houston Methodist Neal Cancer Center, Houston

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: TBD

4:30 – 5:30 pm

Rapid Fire 3
Location: Stars at Night 1 & 2

4:30 – 6:00 pm

Women's Career Development Workshop
Location: 221ABC

Speaker: Anne Welsh

5:00 – 6:30 pm

Poster Session 2
Location: Exhibition Hall

Thursday, December 11

(All times are in Central Standard Time)

7:00 – 8:45 am Poster Spotlight 5

Location: Hemisfair Ballroom 3

Moderator: TBD

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

7:00 – 8:45 am

Poster Spotlight 6
Location: 301 ABC

Moderator: TBD

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

7:00 – 8:45 am

Poster Spotlight 7
Location: 302 ABC

Moderator: TBD

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30-7:50

Panel Q&A 1: 7:50-8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20-8:30

7:00 – 8:45 am

Poster Spotlight 8
Location: 221 ABC

Moderator: TBD

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

8:30 – 9:00 am

Plenary Lecture 1
Location: Hall 1

Moderator: Debra Patt

Partnering with Progress

  • Dennis Slamon, MD, University of California Los Angeles
  • Barbara Segarra-Vazquez, Patient Advocate, University of Puerto Rico
9:00 – 11:30 am

General Session 2
Location: Hall 1

11:30 am – 12:00 pm

AACR Award Lecture
Location: TBD

12:00 – 6:45 pm 

Exhibition Hall Open

12:00 – 12:30 pm

Break

12:00 – 12:50 pm

Molecular Tumor Board
Location: Stars at Night 1 & 2

Moderator: Ben Park, MD, PhD, Vanderbilt-Ingram Cancer Center, Nashville

Topic 1: Med Oncology

  • Mark Burkard, MD, PhD, Iowa Health Care Holden Comprehensive Cancer Center, Iowa City, Iowa

Topic 2: Pathology

  • TBD

Topic 3: Surgery

  • Funda Meric-Bernstam, MD, MD Anderson Cancer Center, Houston

Topic 4: Genetics

  • Susan Domchek, MD, University of Pennsylvania Perelman School of Medicine, Philadelphia

Patient Advocate: Mary Jimenez, BBA, Alamo Breast Cancer Foundation, San Antonio, Texas

12:30 – 2:00 pm Poster Session 3
Location: Exhibition Hall
1:00 – 2:15 pm

State of the Art 2: Targeting the Non-T Cell Microenvironment
Location: Stars at Night 3 & 4

Moderator: Christos Sotiriou, MD, PhD, Institut Jules Bordet, Anderlecht, Belgium

1:05 PM - 1:25 PM Topic 1: Firbroblast and Immunosuppression in Breast Cancer

  • Fatima Mechta-Grigoriou, PhD, Institut Curie, Paris

1:25 PM - 1:45 PM Topic 2: Role of Macrophage Reprogramming in Breast Cancer Outcomes

  • Lisa Coussens, PhD, FAACR, FAIO, Knight Cancer Institute at Oregon Health & Science University, Portland, Oregon

1:45 PM - 2:05 Topic 3: Targeting non-T-cells in the clinic

  • George Plitas, MD, Memorial Sloan Kettering Cancer Center, New York

Patient Advocate: Cheryl Jernigan, CPA, FACHE, University of Kansas Medical Center, Kansas City, Kansas

1:00 – 2:15 pm

Clinical Controversies: Management of the Axilla in Multi-disciplinary Care
Location: Stars at Night 1 & 2

Moderator: Tari King, MD, FACS, Dana-Farber Cancer Institute, Boston

Topic 1: De-escalation of axillary surgery after NAC in clinically node positive patients

  • Giacomo Montagna, MD, MPH, Memorial Sloan Kettering Cancer Center, New York

Topic 2: De-escalation of regional nodal radiation after NAC in clinically node positive patients

  • Lori Pierce, MD, University of Michigan, Ann Arbor, Michigan

Topic 3: Adjuvant therapy decisions in HR+HER2- breast cancer in the era of axillary de-escalation

  • Sherry Shen, MD, Memorial Sloan Kettering Cancer Center, New York

Patient Advocate: Beth Emery, National Breast Cancer Coalition, Irving, Texas

2:30 – 4:15 pm

Educational Session 11 How to Treat TNBC: Triple Negative Not So Negative Anymore
Location: Stars at Night 1 & 2

Moderator: Marleen Kok, MD, PhD, Netherlands Cancer Institute, Amsterdam

2:30 PM-3:00 PM Topic 1: To escalate or de-escalate treatment for Stage 1 TNBC

  • Gustavo Werutsky, MD, Moinhos de Vento Hospital and Executive Director of the Latin American Cooperative Oncology Group, Porto Alegre, Brazil.

3:00 PM-3:30 PM Topic 2: Tailored therapy for stage II and III TNBC

  • Elie El-Rassy, MD, MSc, MPH, Gustave Roussy, Villejuif, France

3:30 PM - 4:00 PM Topic 3: Treatment Updates in metastatic TNBC

  • Sara Tolaney, MD, MPH, Dana-Farber Cancer Institute, Boston

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Janice Cowden, Metastatic Breast Cancer Patient Advocate, North Port, Florida

2:30 – 4:15 pm

Educational Session 12 New Frontiers in Breast Cancer: Targeting Therapy Resistance
Location: Hemisfair Ballroom 1 & 2

Moderator: Qing Zhang, PhD, UT Southwestern Medical Center, Dallas

2:30 PM-3:00 PM Topic 1: Epigenetic regulation in endocrine resistant breast cancer

  • Luca Magnani, PhD, Institute of Cancer Research, London, UK

3:00 PM-3:30 PM Topic 2: Insights in CDK4/6 inhibitor resistance in breast cancer

  • Seth Wander, MD, PhD,  Massachusetts General Hospital, Boston

3:30 PM - 4:00 PM Topic 3: ADC resistance in breast cancer

  • Leif Ellisen, MD, PhD, Massachusetts General Hospital, Boston

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Michelle Audoin, Patient Partner at the Ontario Institute for Cancer Research and patient representative at the Canadian Cancer Trials Group, Toronto

2:30 – 4:15 pm

Educational Session 13 Optimizing Cardiac Outcomes in Breast Cancer: The Next Chapter
Location: 221 ABC

Moderator: Alexandra Thomas, MD, FACP, Duke Cancer Institute, Durham, North Carolina

2:30 PM – 3:00 PM Topic 1: Cardiotoxicity of breast cancer novel therapies

  • Anne Blaes, MD, University of Minnesota Masonic Cancer Center, Minneapolis

3:00 PM – 3:30 PM Topic 2: Approaches for Cardio-protection in Cancer Care

  • Eric Yang, MD, University of California, Los Angeles Medical Center, Los Angeles

3:30 PM – 4:00 PM Topic 3: Developing clinical trials/getting answers in this space

  • Javid Moslehi, MD, University of California, San Francisco

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: AJ Veach, Patient Partner with Savvy Cooperative, Washington, D.C.

2:30 – 4:15 pm

Educational Session 14: Breast Cancer in Young Women - When, Why, and How?
Location: Hemisfair Ballroom 3

Moderator: Christina Curtis, PhD, MSc, Stanford University, Stanford, California

2:30 PM - 3:00 PM Topic 1: When: Molecular epidemiology of breast cancer in young women

  • Melissa Troester, PhD, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

3:00 PM - 3:30 PM Topic 2: Why: Molecular and immunological basis of breast cancer across the age continuum

  • Kornelia Polyak, MD, PhD, Dana-Farber Cancer Institute, Boston

3:30 PM - 4:00 PM Topic 3: How: Genomic and immunologic characteristics of breast cancer in young women

  • Sherene Loi, PhD,  Peter MacCallum Cancer Centre, Melbourne, Australia

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Samantha Horn, Patient Care Specialist, Baltimore, Maryland

2:30 – 4:15 pm

Educational Session 15: Real Impact with Artificial Intelligence
Location: Stars at Night 3 & 4

Moderator: Frederick Howard, MD, University of Chicago Medicine, Chicago

2:30 PM - 3:00 PM Topic 1: Digital Biomarkers and Risk Prediction

  • Johan Hartman, MD, Karolinska Institutet, Solina, Sweden

3:00 PM - 3:30 PM Topic 2: Big Data to Solve Big Problems

  • Tufia Haddad, MD, Mayo Clinic, Rochester, Minnesota

3:30 PM - 4:00 PM Topic 3: A Roadmap for Implementation of AI Tools

  • TBD

4:00 PM - 4:15 PM Panel Q&A

Patient Advocate: Carole Baas, National Advocate, Physical Sciences in Oncology Network, National Cancer Institute, Southlake, Texas

4:30 – 5:30 pm

Rapid Fire 4
Location: Stars at Night 1 & 2

5:15 – 5:45 pm

Refreshment Break and Networking
Location: TBD

5:00 – 6:30 pm Poster Session 4
Location: Exhibition Hall

Friday, December 12

(All times are in Central Standard Time)

7:00 – 8:30 am

Poster Spotlight 9
Location: Hemisfair Ballroom 3

Moderator:

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

7:00 – 8:30 am

Poster Spotlight 10
Location: 301 ABC

Moderator:

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

7:00 – 8:30 am

Poster Spotlight 11
Location: 302 ABC

Moderator:

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

7:00 – 8:30 am

Poster Spotlight 12
Location: 221 ABC

Moderator:

7:00 AM - 7:30 Poster viewing

Subtopic 1: 7:30 - 7:50

Panel Q&A 1: 7:50 - 8:00

Subtopic 2: 8:00 - 8:20

Panel Q&A 2: 8:20 - 8:30

8:30 – 9:00 am

Plenary Lecture 2
Location: Hall 1

Genetic and epigenetic determinants of BRCA1/2 tumorigenesis
Joan Brugge, PhD, Harvard Medical School, Cambridge, Massachusetts

9:00 – 11:30 am

General Session 3
Location:
Hall 1

11:30 am – 12:00 pm AACR Award Lecture
Location: TBD
12:00 – 12:30 pm 

Break

12:00 – 3:00 pm 

Exhibition Hall Open

12:30 – 2:00 pm

Poster Session 5
Location:
Exhibition Hall

1:00 – 2:50 pm

Special Topic Focus: Beyond Cancer - Addressing Body Image, Hair Loss, and Skin Health After Treatment
Location: 221 ABC

Topic 1: Alopecia and Cancer Therapy: Causes, Solutions, and Survivorship Strategies - Understanding treatment-related hair loss, emerging therapies, and access to care.

Topic 2: Managing Skin Toxicities in Cancer Care: Recognition, Treatment, and Prevention - A guide to identifying, assessing, and addressing dermatologic side effects of treatment.

Topic 3: Body Image and Cancer: Coping with Change and Restoring Confidence - Exploring the psychological and physical impact of cancer treatments on body image, and strategies for self-acceptance and empowerment.

Patient Advocate: TBD

2:00 – 2:50 pm

Debate: Do All Early-stage Breast Cancer Patients Need Axillary Staging
Location: Stars at Night 1 & 2

Chair: Elizabeth Mittendorf, MD, PhD, MHCM, Dana-Farber Cancer Institute, Boston

Arguing affirmative: Melissa Pilewskie, MD, Rogel Cancer Center at University of Michigan, Ann Arbor, Michigan

 Arguing Negative: TBD

3:00 – 5:00 pm

Year in Review
Location: Stars at Night 1 & 2

Topic 1: Basic

  • Steffi Oesterich, PhD, UPMC Hillman Cancer Center, Pittsburgh

Topic 2: Translational

  • Fred Howard, MD, University of Chicago Medicine, Chicago

Topic 3: Early Breast Cancer

  • William Gradishar, MD, Northwestern University Feinberg School of Medicine, Chicago

Topic 4: Metastatic Breast Cancer

  • Sonya Reid, Sonya Reid, MD, MPH, Vanderbilt-Ingram Cancer Center, Nashville

5:00 – 5:30 pm

Refreshment Break
Location: TBD

5:30 – 6:30 pm

View from the Trenches
Location: Stars at Night 1 & 2

Moderator: Heather McArthur, MD, MPH, UT Southwestern Medical Center, Dallas

Topic 1: Surgical Oncology

  • Judy Boughey, Mayo Clinic, Rochester, Minnesota 

Topic 2: Radiation Oncology

  • Jonathan Strauss, MD, MBA, Roberts H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago

Topic 3: Medical Oncology

  • Tara Sanft, MD, Yale School of Medicine, New Haven, Connecticut  

Patient Advocate: Julia Maues, It’s Not Pink, Baltimore, Maryland